The 23rd Jerusalem School in Life Sciences

Computational and Structural Biology

Event date: January 10 - January 14, 2016

    General Director: Roger Kornberg (Stanford University )
    Nir Kalisman (The Hebrew University)
    Julia Shifman (The Hebrew University)



    List of Speakers


    David BensimonÉcole Normale Supérieure
    Avinoam Ben ShaulThe Hebrew University of Jerusalem
    Ron DrorStanford University
    Sarel FleishmanWeizmann Institute of Science
    William GelbartUCLA
    Daniel HarriesThe Hebrew University of Jerusalem
    Stephen HarrisonHarvard Medical School
    Tom KirchhausenHarvard Medical School
    Rachel KolodnyUniversity of Haifa
    Michael LevittStanford University
    Emmanuel LevyWeizmann Institute of Science
    Ohad MedaliaUniversity of Zürich  and Ben-Gurion University of the Negev
    Gali PragTel Aviv University
    Tamar SchlickNew York University
    Gideon SchreiberWeizmann Institute of Science
    Ada YonathWeizmann Institute of Science


    Computational Biology and Structural Biology are closely interrelated areas of research. Throughout the years, great advances in experimental techniques resulted in the appearance of multiple structures, including very large and complicated molecular machines. At the same time, computer simulations and analyses allowed for a better understanding of macromolecular modes of action. This mutual importance has been recently highlighted by the Nobel Prize in Chemistry given for “the development of multiscale models for complex chemical systems." The School aims to focus on the ongoing synergy between Computational and Structural Biology. It features a great team of speakers from both fields, including three Nobel laureates. Participants in the School will become familiar with the principles of multiple methods such as: X-ray crystallography and Electron Microscopy of very large structures, Molecular Dynamics, Computational Protein Design, QM/MM, Structural Classification, and Biophysics. In parallel, the state-of-the-art applications of these techniques to outstanding biological problems will be presented.